Which facial feature is commonly associated with Down syndrome?

• A. Up-slanting palpebral fissures
• B. Broad nasal bridge
• C. Short philtrum
• D. Protruding ears

Answer: (A)

Upslanted palpebral fissures describe the outward tilt of the eyes, where the outer corners sit higher than the inner corners. This eye shape is one of the most recognizable facial patterns in Down syndrome and often appears with other facial traits like epicanthal folds, contributing to the distinctive look clinicians associate with the condition.

Other features listed don’t align as closely with the typical Down syndrome facial profile. The nasal bridge tends to be flattened rather than broad, giving a different nasal appearance. A short philtrum and protruding ears are not defining hallmarks of the condition and are less reliable clues on their own.